Producing protocols, creating common standards

COG-UK members are working together to develop common, best-practice protocols, methods and techniques to prepare collect and prepare SARS-CoV-2 virus samples for sequencing, conduct short-read and long-read sequencing at scale with minimal turnaround times, and speed the flow of whole-genome data to open-access databases and online visualisation platforms. - the canonical source for COG-UK consortium protocols

All protocols, standards and techniques will be shared between COG-UK members through the online platform.

All documentation is disseminated at:

Below is a list of the current protocols:

nCoV-2019 sequencing protocol v3 (LoCost)

Authors: Josh Quick

Published: 25 Aug 2020

COVID-19 ARTIC v3 Illumina library construction and sequencing protocol

Authors: DNA Pipelines R&D, Benjamin Farr, Diana Rajan, Emma Betteridge, ..., Ian Johnston

Published: 29 May 2020