National Studies

The consortium is contributing to a number of national studies to understand more about the transmission and evolution of SARS-CoV-2


The COG-UK HOCI study

The COG-UK HOCI study is investigating how integrating rapid, real-time COVID-19 genomic sequencing can impact decision-making by infection control teams to prevent the spread of the SARS-CoV-2 virus in NHS hospitals.

‘Investigating a vaccine’ study

The ‘Investigating a vaccine against COVID-19’ study aims to assess whether healthy people can be protected from COVID-19 with a new vaccine called ChAdOx1 nCoV-19 — providing information on the safety of the vaccine and its ability to generate good immune responses against SARS-CoV-2.  

The GenOMICC study

GenOMICC is an open, collaborative, global community of doctors and scientists trying to understand and treat critical illness. Partners in the study have been recruiting patients since 2016 to study emerging infections (SARS/MERS/Flu), sepsis, and other forms of critical illness. It is the largest study of its kind anywhere in the world.

The Real-time Assessment of Community Transmission (REACT) Study

REACT (REal-time Assessment of Community Transmission) is a series of studies that are using home testing to improve our understanding of how the COVID-19 pandemic is progressing across England.

The Office of National Statistics (ONS) COVID-19 Infection Survey (CIS)

The overall purpose of this study is to understand how many people of different ages across the UK have already had COVID-19, even if they do not know they had it.

The SARS-CoV-2 Immunity & REinfection EvaluatioN (SIREN) Study

The SIREN study is investigating the impact of detectable anti SARS-CoV-2 antibody on the incidence of COVID-19 in healthcare workers.

The VIVALDI study

The aim of this study is to find out how many care home staff and residents have been infected with COVID-19, to inform decisions around the best approach to COVID-19 testing in the future.

COG-UK data in UK Trusted Research Environments

We work with partners to ensure COG-UK SARS-CoV-2 sequencing data is available in a number of trusted research environments.